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DeCS
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Descriptor English:
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Etoposide
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Descriptor Spanish:
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Etopósido
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Descriptor Portuguese:
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Etoposídeo
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Synonyms English:
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Celltop
Eposide
Eposin
Eto-GRY
Etomedac
Etopos
Etoposide Pierre Fabre
Etoposide Teva
Etoposide, (5S)-Isomer
Etoposide, (5a alpha)-Isomer
Etoposide, (5a alpha,9 alpha)-Isomer
Etoposide, alpha-D-Glucopyranosyl Isomer
Etoposido Ferrer Farma
Exitop
Lastet
NSC-141540
Onkoposid
Riboposid
Toposar
VP 16-213
VP-16
Vepesid
Vépéside-Sandoz
Eto GRY
Etoposide, alpha D Glucopyranosyl Isomer
NSC 141540
NSC141540
Teva, Etoposide
VP 16
VP 16 213
VP 16213
VP16
Vépéside Sandoz
alpha-D-Glucopyranosyl Isomer Etoposide
Demethyl Epipodophyllotoxin Ethylidine Glucoside
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Tree Number:
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D02.455.426.559.847.638.960.675.250
D04.615.638.960.675.250
D09.408.348.275
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Definition English:
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A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. |
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Pharmacological Action:
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Antineoplastic Agents, Phytogenic
Topoisomerase II Inhibitors
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History Note English:
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87(81); was see under PODOPHYLLOTOXIN 1981-86; was VP 16-213 see under PODOPHYLLOTOXIN 1976-80
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Allowable Qualifiers English:
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Record Number:
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5143
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Unique Identifier:
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D005047
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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